Efficacy and Safety of Fecal Microbiota Transplantation in Radiation Enteritis

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Radiation enteritis is one of the most feared complications after abdominal or pelvic radiation therapy.The gut microbiota is considered to constitute a microbial organ which has pivotal roles in the intestinal diseases and body metabolism. Evidence from animal studies demonstrated the link between intestinal bacteria and radiation enteritis. This clinical trial aims to evaluate the efficacy and safety of fecal microbiota transplantation (FMT) for radiation enteritis.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:

• age ≥18 years old;

• Radiation enteritis diagnosed by colonoscopy after finishing radiotherapy.

Locations
Other Locations
China
Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University
RECRUITING
Nanjing
Contact Information
Primary
Faming Zhang, MD; PHD
fzhang@njmu.edu.cn
086-25-58509883
Time Frame
Start Date: 2018-01-07
Estimated Completion Date: 2025-07-01
Participants
Target number of participants: 70
Treatments
Experimental: Fecal Microbiota Transplantation (FMT)
Patients receive a course of FMT during hospitalization
No_intervention: Basic treatment
Patient receives basic therapy for RE during hospitalization
Sponsors
Collaborators: Jiangxi Provincial Cancer Hospital
Leads: The Second Hospital of Nanjing Medical University

This content was sourced from clinicaltrials.gov

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