A Study of the Clinical Application of [18F]RCCB6 and [68Ga]Ga-NOTA-RCCB6 PET/CT Imaging in the Diagnosis of CD70-expressing Multiple Tumors
Status: Recruiting
Location: See location...
Intervention Type: Radiation
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The aim of this study was to establish and optimize the \[18F\]RCCB6 and \[68Ga\]Ga-NOTA-RCCB6 PET/CT imaging method, and its physiological and pathological distribution characteristics, on the basis of which the diagnostic efficacy of the above imaging agents in renal cancer (especially clear cell renal cell carcinoma) and lymphoma was evaluated.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
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• Be between 18 and 65 years of age and of either sex.
• Affected with renal cancer or lymphoma confirmed by puncture or surgical pathology.
• Informed consent must be signed in writing by the subject or his/her legal guardian or caregiver.
• Willingness and ability to cooperate with all programs of this study.
Locations
Other Locations
China
Huashan Hospital
RECRUITING
Shanghai
Contact Information
Primary
Yihui Guan, MD
guanyihui@hotmail.com
13764308300
Time Frame
Start Date: 2023-10-01
Estimated Completion Date: 2024-09-01
Participants
Target number of participants: 20
Treatments
Experimental: patients with renal cancer
Intravenous injection of 3.7 MBq \[0.1 mCi\]/kg of \[18F\]RCCB6 or \[68Ga\]Ga-NOTA-RCCB6 in a single dose
Experimental: patients with lymphoma
Intravenous injection of 3.7 MBq \[0.1 mCi\]/kg of \[18F\]RCCB6 or \[68Ga\]Ga-NOTA-RCCB6 in a single dose
Related Therapeutic Areas
Sponsors
Leads: Huashan Hospital