Contribution of Nasal High Flow in Pneumology Assessed in Acid-Free Hypercapnic Acute Respiratory Failure

Status: Terminated
Location: See all (3) locations...
Intervention Type: Device, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The hypothesis is that Nasal High Flow therapy for patients with Hypercapnic Acute Respiratory Failure without acidosis, in addition to standard treatment would improve the care.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Major patient ≥ 18 years old

• Medical diagnosis of Acute Respiratory Failure less than 48 hours

• With partial pressure of carbon dioxide (PaCO2) \> 45 and pH \> 7.35 for less than 48 hours, with no indication of Non-Invasive Ventilation (NIV) placement

• Underlying terrain of known or unknown chronic respiratory pathology (may be unknown at time of diagnosis) Examples : COPD, Bronchiectasis, Pulmonary fibrosis, asthma, sequelae pathologies …

• All etiologies (infectious, cardiac decompensation, trauma, etc.)

• Having given informed consent

• Patient under a social security scheme

• Possibility to include a patient having already been included in the study but suffering from a new episode of hypercapnic non acidic Acute Respiratory Failure with a free interval of 3 months

Locations
Other Locations
France
Centre Hospitalier de Cannes
Cannes
Centre Hospitalier Intercommunal de Toulon- La Seyne sur Mer - Hôpital Sainte Musse
Toulon
Monaco
Centre Hospitalier Princesse Grace
Monaco
Time Frame
Start Date: 2024-02-27
Completion Date: 2025-09-24
Participants
Target number of participants: 16
Treatments
Experimental: Nasal High Flow therapy in association with the standard therapy
Active_comparator: Standard therapy alone
Related Therapeutic Areas
Sponsors
Leads: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer

This content was sourced from clinicaltrials.gov