Clinical Features Associated With Restless Legs Syndrome : Clin-RLS

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Restless legs syndrome (RLS) is a chronic neurological disorder characterized by an urge to move the legs at night when at rest. RLS can lead to a sleep deprivation, increased falling risk, daytime sleepiness, depression and decreased quality of life. Dopamine agonists, alpha-2-delta ligands and opiates are key medications for RLS. The natural course of RLS is very heterogeneous with a risk of increasing the severity of symptoms over the years despite the use of drugs and recommended dosages. Many comorbidities can make RLS worse. Augmentation syndrome is the main complication of dopamine agonists. However, only a few studies have addressed the clinical, biological and pharmacological factors associated with the evolution of the severity of RLS. The objective of this study is to assess the evolution of RLS symptoms severity as function of RLS phenotype, comorbidities and RLS medication, in large cohort of members of the French RLS association and other European RLS association.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adults subjects

• Restless legs syndrome diagnosis

• Member of the restless legs syndrome association

• French speaking

• Able to understand the study

• Signed written informed consent

• Affiliated to social security

Locations
Other Locations
France
Uhmontpellier
RECRUITING
Montpellier
Contact Information
Primary
Sofiene Chenini, MD
sofienechenini@hotmail.com
467332237
Backup
Yves DAUVILLIERS, MD PhD
y-dauvilliers@chu-montpellier.fr
467337478
Time Frame
Start Date: 2021-09-01
Estimated Completion Date: 2027-09-01
Participants
Target number of participants: 2000
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Montpellier

This content was sourced from clinicaltrials.gov