A Single Arm No-treatment Self-controlled Trial Pilot Study Evaluating the Clinical Efficacy and Safety Profile of 20% Cassia Alata Cream Against Tinea Versicolor

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1
SUMMARY

The goal of this clinical trial is to establish the efficacy of Cassia alata extract as a cream form in treating tinea versicolor (liver spots/shifting clouds). The main questions the study aims to answer are:• Does the use of this extract help resolve tinea versicolor better than no treatment? Does the use of this cream have significant side effects i.e, is it safe? Participants will be asked to treat a designated area while leaving additional areas untreated. 1-2 finger tip units of cream will be applied to the treatment site twice daily at least 8 hours apart. Participants will attend the trial clinic every 4 weeks for 12 weeks.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 89
Healthy Volunteers: f
View:

• Patients aged 18-89 of either sex

• Clinical features suggestive of tinea versicolor AND Microscopic confirmation using skin scraping stains with chlorazol black preparation AND/OR Wood's lamp fluorescence

• No treatment for versicolor in the preceding 4 weeks

• No contraindications to the application of C.alata cream including

• No history of allergy to C. alata

• No history of preservative allergy

Locations
Other Locations
Jamaica
University of the West Indies, Mona
RECRUITING
Kingston
Contact Information
Primary
Marvin Reid, MB Bs PhD
marvin.reid@uwimona.edu.jm
8763812939
Time Frame
Start Date: 2025-03-01
Estimated Completion Date: 2026-12-30
Participants
Target number of participants: 20
Treatments
Experimental: Treatment
Participants with tinea versicolor who will have a treatment site selected. We will leave untreated areas to serve as internal controls. Participants will apply cream to the designated areas but leave non-designated untreated. At follow up visits we will do fungal scrapings, visual examination and Wood's lamp evaluation of treatment and non-treatment areas
Related Therapeutic Areas
Sponsors
Leads: The University of The West Indies

This content was sourced from clinicaltrials.gov