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The Efficacy and Safety of Anti-inflammation Treatment (Hirudoid Introduction Followed by Yellow Light Therapy) Combined With Tofacitinib and Doxycycline in Chinese Adult Patients With Mild to Moderate Erythematous Telangiectatic Rosacea: A Prospective Parallel Controlled Single-blind Cohort Study

Status: Recruiting
Location: See location...
Intervention Type: Drug, Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The efficacy and safety of anti-inflammation treatment (Hirudoid introduction followed by yellow light therapy) combined with tofacitinib and doxycycline in Chinese adult patients with mild to moderate erythematous telangiectatic rosacea: A prospective parallel controlled single-blind cohort study

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:

• The subjects are male or female, aged 18 to 70 years (inclusive); they voluntarily participate in this study and sign the informed consent form.

• They are diagnosed with erythematous telangiectatic rosacea, meeting the diagnostic criteria in the Chinese Guidelines for the Diagnosis and Treatment of Rosacea (2021).

• At screening and baseline, the IGA score is 2 (mild) or 3 (moderate).

• The subjects agree not to use any other rosacea treatment drugs (prescription or over-the-counter) during the study period.

• The subjects are willing to minimize external factors that may trigger rosacea (such as spicy food, alcoholic beverages, prolonged sun exposure, etc.).

• The subjects (including their partners) agree that they have no plans to conceive within 3 months after signing the informed consent form until the end of the last treatment and are willing to take effective contraceptive measures voluntarily.

Locations
Other Locations
China
The Fourth Affiliated Hospital of Zhejiang University School of Medicine
RECRUITING
Yiwu
Contact Information
Primary
Liu
2197055@zju.edu.cn
0579-89979999
Time Frame
Start Date: 2026-02-01
Estimated Completion Date: 2027-07-01
Participants
Target number of participants: 186
Treatments
Active_comparator: Control group
Participants receive doxycycline combined with hydroxychloroquine.
Active_comparator: Tofacitinib group
Participants receive doxycycline combined with tofacitinib.
Experimental: Anti-inflammation Treatment and Tofacitinib group
Participants receive doxycycline and tofacitinib combined with anti-inflammatory treatment.
Related Therapeutic Areas
Sponsors
Leads: The Fourth Affiliated Hospital of Zhejiang University School of Medicine

This content was sourced from clinicaltrials.gov