• Male or female 18+ years of age at the time of signed informed consent;

• SSc classification as defined by the 2013 American College of Rheumatology/European League Against Rheumatism criteria. Participants with diffuse, limited or sine cutaneous skin involvement are eligible

• Onset of SSc (defined by first non-Raynaud's symptom) 7 years or less prior to the Screening Visit;

• A Modified Rodnan skin score (mRSS) less than 40

• Presence of ILD with evidence of any fibrosis on HRCT (within 3 months or less of randomization)

• Presence of an FVC 45% or more predicted normal;

• Presence of a diffusing capacity of the lung for carbon monoxide (DLCO) 30% or more predicted normal, corrected for hemoglobin;

⁃ Other protocol and/or subprotocol inclusion criteria apply.