Application of Ultrasound Shear Wave Elastography on the Adjunct Corticosteroid Therapy on Tuberculous Lymphadenitis: a Randomized Control Trial

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

1. To prospectively collect the radiologic data from the initial phase till the post-treatment phase of tuberculous lymphadenitis. 2. To prospectively investigate the benefits of corticosteroid on reduction of paradoxical upgrading reaction in patients with tuberculous lymphadenitis based on the results of shear wave elastography. 3. To investigate the potential biomarker of host immunity in response to tuberculosis and predict the development of paradoxical upgrading reaction.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Participants diagnosed of tuberculous lymphadenitis.

• The diagnosis of tuberculous lymphadenitis must qualify any of the following criteria:

‣ microbiological evidence (culture or nucleic acid amplification test)

⁃ histology specimen featuring caseating granulomatous inflammation with acid-fast bacilli on smear, or clinical response to anti-tuberculosis therapy.

Locations
Other Locations
Taiwan
National Taiwan University Hospital
RECRUITING
Taipei
Contact Information
Primary
Yen-Lin Chen
moich1@ntuh.gov.tw
0972651876
Backup
Yen-Lin Chen
moich.chen@gmail.com
0972651876
Time Frame
Start Date: 2023-05
Estimated Completion Date: 2025-12
Participants
Target number of participants: 50
Treatments
Experimental: Adjunct corticosteroid and standard anti-tuberculosis agent
Prednisolone dosing and duration per study protocol
Active_comparator: Standard of care with standard anti-tuberculosis agent
standard anti-tuberculosis agent
Related Therapeutic Areas
Sponsors
Leads: National Taiwan University Hospital

This content was sourced from clinicaltrials.gov

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