The Effects of Oral Vitamin D Supplementation on the Prevention of Peritoneal Dialysis-related Peritonitis, a Multicenter Randomized Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
This is a multicenter randomized, placebo-controlled trial of Vitamin D supplementation in patients on peritoneal dialysis to determine whether oral administration of vitamin D3 after curing an episode of peritonitis could reduce the risk of subsequent peritoneal dialysis-related peritonitis.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 19
Healthy Volunteers: f
View:
• Medically stable and receiving peritoneal dialysis for \> 1 month
• Older than 18 years old
• Serum 25(OH)D \< 30ng/ml
• Adequate dialysis on evaluation with weekly Kt/V ≥ 1.5, or (revised time: 2023-7-11) without clinical uremic symptoms
Locations
Other Locations
China
Peking University First Hospital
RECRUITING
Beijing
Contact Information
Primary
Jie Dong, Professor
jie.dong@bjmu.edu.cn
13911841538
Backup
Zhikai Yang
seapollar@126.com
13671248465
Time Frame
Start Date: 2023-06-15
Estimated Completion Date: 2026-05-31
Participants
Target number of participants: 176
Treatments
Active_comparator: Treatment group
Patients will be given Cholecalciferol (produced by Xymogen Company) 4000 U (2 capsules) per day
Placebo_comparator: Control group
Patients will receive placebo, 2 capsules per day.
Related Therapeutic Areas
Sponsors
Collaborators: Capital Medical University, Beijing Anzhen Hospital, Beijing Fangshan District Hospital of Traditional Chinese Medicine, Beijing Tsinghua Changgeng Hospital, Beijing Haidian Hospital, Peking University Third Hospital, Peking University International Hospital, Peking University Shenzhen Hospital, Miyun District of Peking University First Hospital, Peking University People's Hospital
Leads: Peking University First Hospital