Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Electrographic seizures are common in critically ill patients leading to increased use of resource-intense continuous EEG monitoring for seizure identification and management. When identified, electrographic seizures are generally treated with anti-seizure medications, but there are very limited data available regarding optimal treatment in terms of the efficacy or safety of specific anti-seizure medications or overall management strategies. This is a single-center prospective observational study. The investigators aim to: (1) track critically ill patients undergoing clinically indicated EEG monitoring and seizure management to identify risk factors for electrographic seizures, (2) create prediction models guiding EEG monitoring resources to the patients at highest risk for seizures, and (3) evaluate our current management strategy in terms of safety.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 1 month
Maximum Age: 18
Healthy Volunteers: f
View:

• Care in the Children's Hospital of Philadelphia Pediatric ICU.

• Clinically indicated continuous EEG monitoring.

• Age \> 1 month to 18 years.

Locations
United States
Pennsylvania
Children's Hospital of Philadelphia
RECRUITING
Philadelphia
Contact Information
Primary
Nicholas S Abend, MD
abend@chop.edu
215-590-1719
Time Frame
Start Date: 2017-03-13
Estimated Completion Date: 2027-01-01
Participants
Target number of participants: 2500
Treatments
Cohort
Critically ill child undergoing clinically indicated EEG monitoring and electrographic seizure management.
Related Therapeutic Areas
Sponsors
Leads: Children's Hospital of Philadelphia
Collaborators: National Institute of Neurological Disorders and Stroke (NINDS)

This content was sourced from clinicaltrials.gov