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Cognitive and Functional Telehealth-based Assessment and Intervention in Veterans With Psychogenic Nonepileptic Seizures

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Psychogenic nonepileptic seizures (PNES) reflect a subtype of functional neurological disorder (FND) that is common and extremely disabling in Veterans. Cognitive problems are highly prevalent in PNES, they reduce quality of life, and they severely limit daily functioning. Currently, there are no available treatments that target cognition to improve daily function in PNES or other FNDs, leaving a major gap in the literature. Cognitive re-habilitation improves daily functioning in Veterans with related neuropsychiatric disorders and has a high chance of success in Veterans with PNES. The proposed study will solicit direct input from Veterans with PNES via qualitative interviews to inform the design of a cognitive treatment workbook. The workbook will then be iteratively refined based on participatory feedback from Veterans with PNES and their treatment providers. The full cognitive intervention protocol will be pilot tested to inform a fully powered RCT. Results will support a line of research that aims to improve cognition and function in Veterans with PNES and related FNDs.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• U.S. Veteran

• able to provide informed consent

• reports cognitive difficulties

• prior video EEG diagnosis of PNES

• English speaking

• able to read at least at 8th grade level

• access to a private space with a computer (13-inch monitor)

• internet access

Locations
United States
Rhode Island
Providence VA Medical Center, Providence, RI
RECRUITING
Providence
Contact Information
Primary
Madeleine R Lefkowitz, BS
Madeleine.Lefkowitz@va.gov
(401) 127-7100
Backup
Alison Gorbatov
Alison.Gorbatov@va.gov
(401) 271-7100
Time Frame
Start Date: 2026-03-02
Estimated Completion Date: 2031-07-01
Participants
Target number of participants: 47
Treatments
Other: Intervention
Single arm of pilot trial testing the cognitive rehabilitation intervention
Related Therapeutic Areas
Sponsors
Leads: VA Office of Research and Development

This content was sourced from clinicaltrials.gov

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