A Real-world Study of the Efficacy and Safety of PEGylated Recombinant Human Growth Hormone Injection in the Treatment of Short Stature in Chinese Children From the Global Registry for Novel Therapies For Rare Bone or Endocrine Conditions
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Observational
SUMMARY
In order to further observe the long-term safety and effectiveness of real-world polyethylene glycol-recombinant human growth hormone(PEG-rhGH) treatment of GHD, idiopathic short stature, and SGA in children, explore and analyze the factors affecting the efficacy of PEG-rhGH and the height prediction model after treatment, etc., collect and analyze more scientifically and rationally, and understand the situation of real-world PEG-GH treatment. A database registration study was developed.
Eligibility
Participation Requirements
Sex: All
Maximum Age: 18
Healthy Volunteers: f
View:
• Patients with endogenous growth hormone deficiency, Turner Syndrome, SGA, idiopathic short stature, etc. treated with polyethylene glycol recombinant human growth hormone injection
Locations
Other Locations
China
Department of Endocrinology, Genetics, Metabolism
RECRUITING
Beijing
Contact Information
Primary
Chunxiu Gong, Dr.
chunxiugong@163.com
13370115001
Backup
Jiajia Chen, Dr.
chenjiaj2009@126.com
13810773718
Time Frame
Start Date: 2023-08-01
Estimated Completion Date: 2029-08-01
Participants
Target number of participants: 2600
Treatments
growth hormone deficiency(GHD)
Growth hormone deficiency (GHD) is a rare and treatable condition that causes short height in children and metabolic issues in adults.
Idiopathic short stature (ISS)
Idiopathic short stature is a condition in which the height of the individual is more than 2 SD below the corresponding mean height for a given age, sex and population, in whom no identifiable disorder is present.
small for gestational age (SGA)
Small for gestational age (SGA) is defined as a birth weight of less than 10th percentile for gestational age.
Turner Syndrome (TS)
Turner syndrome, a condition that affects only females, results when one of the X chromosomes (sex chromosomes) is missing or partially missing.
others
others who with the height of the individual is more than 2 SD below the corresponding mean height for a given age, sex and population.
Related Therapeutic Areas
Sponsors
Collaborators: University of Glasgow
Leads: Beijing Children's Hospital