Operant Conditioning of the Soleus Stretch Reflex in Adults With Cerebral Palsy

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

12 adults with spastic CP will complete 6 baseline sessions and 24 down conditioning sessions held 3 times/week. All clinical and physiological assessments collected at baseline will be reassessed after study completion, and follow ups after 2 weeks, 1 month and 3 months. The soleus H reflex (electric analogue of the stretch reflex) will be elicited in all sessions. In each session, participants will complete 20 baseline trials and 225 down conditioning trials to decrease the magnitude of the H-Reflex.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Age 18 and above

• Diagnosis of spastic Cerebral Palsy

• Gross Motor Function Classification System level I-III

• Stable medical background

• Current medication will remain unchanged for 3 months

• Provides informed consent

• can walk at least 10 meters with or without assistive device

• meets minimum study procedure requirements (elicitation of H-reflex).

Locations
United States
New York
Burke Neurological Institute
RECRUITING
White Plains
Contact Information
Primary
Devina Kumar, PhD
dek4004@med.cornell.edu
914-368-3160
Time Frame
Start Date: 2022-09-30
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 12
Treatments
Experimental: Spinal reflex conditioning
The OC intervention includes 6 baseline sessions and 24 conditioning/ no conditioning sessions held 3 times/week.~To elicit an H-reflex, participants will be asked to stand in a comfortable position. Small pulses of energy will be applied to a nerve in the leg called the tibial nerve. We will record when the participant maintains leg muscle activity. During the intervention, participants will be trained to decrease their reflex in their calf.
Related Therapeutic Areas
Sponsors
Leads: Burke Medical Research Institute

This content was sourced from clinicaltrials.gov