Differential Assessment of Hypertonia Related to CNS Impairment

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Spasticity and rigidity are common symptoms of central nervous system injuries, such as spinal cord injury and Parkinson's disease, and result in distinct patterns of increased resistance during passive joint movements. Spasticity is characterized by a velocity-dependent increase in stretch reflexes, accompanied by exaggerated tendon responses, while rigidity is marked by consistent resistance throughout the range of motion, traditionally considered independent of stretch velocity. However, recent studies suggest that rigidity may also be influenced by stretch velocity. This study aims to investigate muscle tone by examining spasticity, rigidity, and normal muscle function through neural and biomechanical changes. Standard clinical tools, such as the Modified Ashworth Scale and Unified Parkinson's Disease Rating Scale, along with additional assessments like the Myoton and Post-Activation Depression (PAD), will be employed.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Healthy Volunteers: t
View:

• \- Clinical diagnosis of Parkinson disease.

Locations
Other Locations
Taiwan
Chang Gung University
RECRUITING
Taoyuan District
Contact Information
Primary
Ya-Ju Chang, PhD
yjchang@mail.cgu.edu.tw
+88632118800
Time Frame
Start Date: 2024-10-09
Estimated Completion Date: 2026-08
Participants
Target number of participants: 45
Treatments
Experimental: Healthy Participants
To establish the relationship between changes in foot pressure during ankle joint movement, muscle tone, and Post-Activation Depression (PAD).
Experimental: PD Patients
To establish the relationship between changes in foot pressure during ankle joint movement, muscle tone, and Post-Activation Depression (PAD).
Experimental: SCI Patients
To establish the relationship between changes in foot pressure during ankle joint movement, muscle tone, and Post-Activation Depression (PAD).
Sponsors
Leads: Chang Gung University

This content was sourced from clinicaltrials.gov