Task Practice Combined With Transcutaneous Spinal Cord Stimulation to Reduce Muscle Co-contraction and Improve Motor Function in Chronic Spinal Cord Injury

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this study is to understand the effects of combined task practice with transcutaneous cervical spinal cord stimulation. The study will explore the effect of higher stimulation frequencies on spasticity. Transcutaneous stimulation has been shown to improve motor function in some individuals with chronic spinal cord injury. The study intends to explore scientifically the association between higher stimulation frequencies and spasticity/hypertonicity.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 22
Maximum Age: 70
Healthy Volunteers: f
View:

• 22-70 years of age

• Non-progressive cervical spinal cord injury

• Minimum 12 months year post-injury.

• American Spinal Injury Association (ASIA) Impairment Scale (AIS) classification B, C, or D.

• Able to take part in upper extremity therapy procedures.

• GRASSP-Prehension score ≥10.

• MAS Score ≥3 but \<6 in at least one arm.

• Can commit to the time required for the study.

• Stable medication profile for at least 4 weeks prior to enrollment.

• Able to reduce Baclofen dose to 30 mg or less daily.

• Capable of providing informed consent.

Locations
United States
Florida
University of Miami - Christine E. Lynn Rehabilitation Center
RECRUITING
Miami
University of Miami, Miller School of Medicine, The Miami Project To Cure Paralysis
RECRUITING
Miami
Contact Information
Primary
Nilanjana Datta, MD
nx693@med.miami.edu
3052436798
Time Frame
Start Date: 2024-09-01
Estimated Completion Date: 2027-10-01
Participants
Target number of participants: 6
Treatments
Experimental: Task Practice with stimulation
Participants in this group will receive combined Transcutaneous cervical spinal cord stimulation with task practice for up to 2 months.
Related Therapeutic Areas
Sponsors
Collaborators: United States Department of Defense, ONWARD Medical, Inc.
Leads: University of Miami

This content was sourced from clinicaltrials.gov