Effects of Transcutaneous Cervical Spinal Cord Stimulation on Upper Limb Motor Function After Traumatic Brain Injury

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this study is to test the effects of non-invasive electrical stimulation of the spinal cord (called transcutaneous spinal cord stimulation, or tSCS) on arm and hand movement in people with motor impairments after a traumatic brain injury (TBI). Specifically, tSCS will be delivered using adhesive electrode pads placed on the skin over the upper back. The research team will measure how tSCS affects strength, movement control and muscle spasticity using different tests. Results of this study will help develop future treatments using an implanted (invasive) form of spinal cord stimulation to improve arm and hand function, helping people with TBI become more independent and improve their quality of life.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Maximum Age: 70
Healthy Volunteers: t
View:

⁃ TRAUMATIC BRAIN INJURY (TBI) SUBJECTS:

• Participants must have a suffered a traumatic brain injury resulting in impairments in arm and hand motor function at least one year prior to enrollment.

• Participants must be between the ages of 21 and 70 years old.

⁃ HEALTHY CONTROL SUBJECTS:

• Participants must have full range of motion in their upper limbs;

• Participants must be between the ages of 21 and 70 years old.

Locations
United States
Pennsylvania
University of Pittsburgh
RECRUITING
Pittsburgh
Contact Information
Primary
Amy Boos, MS
amy.boos@pitt.edu
412-648-4179
Backup
Roberto M de Freitas, PhD
rmd110@pitt.edu
412-383-1077
Time Frame
Start Date: 2025-11-01
Estimated Completion Date: 2029-11-01
Participants
Target number of participants: 80
Treatments
Experimental: Transcutaneous electrical stimulation of the cervical spinal cord (tSCS)
Related Therapeutic Areas
Sponsors
Collaborators: Chuck Noll Foundation
Leads: Roberto de Freitas

This content was sourced from clinicaltrials.gov