Efficacy and Tolerability of Cryoneurolysis Treatment in Disabling and/or Painful Hypertonia of the Shoulder and Elbow in Patients With Cerebral Palsy Who Have Reached a Therapeutic Impasse a Pilot Study

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The main objective of this study is to evaluate the achievement of personalised short- and medium-term objectives of this selective treatment of hypertonia by ultrasound-guided perineural percutaneous cryoneurolysis at the shoulder and elbow, in a population of patients with cerebral palsy with spastic, dyskinetic or dyskinetic, or mixed disorders.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 12
Healthy Volunteers: f
View:

• Patients with cerebral palsy treated at the CMCR des Massues, regardless of their functional status as defined by their gross motor function level on the GMFCS (Gross Motor Function Classification System) and their manual ability level on the MACS (Manual Ability Classification System).

• Presenting with disabling and/or painful muscle hyperactivity in the shoulder and/or elbow,

• Aged over 12 years,

• At a therapeutic impasse: contraindicated or refusing surgery, contraindication or insufficient efficacy of oral treatments (analgesics, baclofen, Artane), too short duration of efficacy of toxin injections (\<3 months) and/or dose-weight limitation not allowing treatment of all necessary sites.

• Patient (and legal representatives in the case of a minor patient or guardian/curator in the case of an adult patient under legal protection measures) who has been informed and has signed the informed consent form for participation in the research,

• Patient affiliated with a social security scheme.

Locations
Other Locations
France
CMCR des Massues
RECRUITING
Lyon
Time Frame
Start Date: 2025-12-22
Estimated Completion Date: 2028-12-15
Participants
Target number of participants: 40
Treatments
Experimental: Cryoneurolise treatment
After testing the function following treatment with a motor block, the patient receives an indication for cryoneurolysis treatment.
Related Therapeutic Areas
Sponsors
Leads: Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française

This content was sourced from clinicaltrials.gov