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Comparative Study on the Value of Three DWI Scan Sequences of 3.0T Magnetic Resonance in Staging of Gastric Cancer

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Accurate staging is critical for effective gastric cancer treatment planning. Conventional DWI (C-DWI) has limitations in image quality due to magnetic field inhomogeneity, which hampers precise T staging. This study aims to compare the image quality and T staging accuracy of C-DWI, TSE-DWI, and ZOOMit-DWI (Z-DWI) sequences in MRI examinations of gastric cancer patients. A prospective study plan to enroll 72 gastric cancer patients undergoing preoperative MRI with C-DWI, TSE-DWI, and Z-DWI sequences using a 3.0 T scanner. Quantitative metrics (ADC, SNR, CNR) and image quality were evaluated. T staging accuracy was assessed by comparing MRI results with postoperative pathological staging using ROC analysis.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: t
View:

• The patient was diagnosed with gastric cancer by pathological biopsy

• No biopsy was taken within 1 week before MR Examination to rule out the effect of bleeding on the image

• No contraindications for MRI examination; And exclude serious heart, liver, kidney, cerebrovascular diseases.

Locations
Other Locations
China
Yunnan Cancer Hospital
RECRUITING
Kunming
Contact Information
Primary
Li Yanli, master
lyl2241@163.com
18987958050
Backup
Li Zhenhui, MD
lizhenhui@kmmu.edu.cn
13698736132
Time Frame
Start Date: 2023-12-23
Estimated Completion Date: 2024-12-31
Participants
Target number of participants: 129
Treatments
No_intervention: SS-EPI-DWI T-stage of gastric cancer
Other: TSE-DWI T-stage of gastric cancer
Other: ZOOM-DWI T-stage of gastric cancer
Related Therapeutic Areas
Sponsors
Leads: Yunnan Cancer Hospital

This content was sourced from clinicaltrials.gov