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Prospective Validation of a CT Radiomics-Based Model Combined With Clinical Features for Prognosis Prediction in Gastric Cancer Patients

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

The goal of this prospective observational study is to evaluate how well a previously developed prediction model can estimate outcomes in adults with gastric cancer. The model combines information from computed tomography (CT) images obtained before treatment with routine clinical information. The main questions are how well the model predicts how long participants live after treatment begins and whether their cancer progresses. Participants will receive their usual medical care. Researchers will collect pretreatment CT images, basic clinical and tumor information, laboratory and tumor marker results, treatment information, and follow-up outcomes obtained during routine care. These data will be entered into the predefined prediction model, and the model's predictions will be compared with what actually happens during follow-up. The study will not change the participants' usual treatment. Model predictions will be used for research purposes only and will not be used to make treatment decisions.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Histologically or pathologically confirmed gastric cancer and receiving treatment at the study center.

• Age ≥18 years.

• Complete pretreatment CT imaging data available from the study center.

Locations
Other Locations
China
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITING
Wuhan
Time Frame
Start Date: 2026-04-01
Estimated Completion Date: 2027-04-01
Participants
Target number of participants: 600
Treatments
Prospective Gastric Cancer Validation Cohort
Adults with newly diagnosed gastric cancer will be prospectively enrolled at the study center. Eligible participants will have pretreatment CT imaging and relevant clinical data available for analysis. Participants will receive routine clinical care according to their clinical condition. Pretreatment CT imaging and clinical data will be analyzed using the predefined prognostic model, and model predictions will be compared with observed clinical outcomes during follow-up.
Related Therapeutic Areas
Sponsors
Leads: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

This content was sourced from clinicaltrials.gov