A Single-Blind, Randomized Study of the BTL EmsellaTM Chair Versus Sham for the Treatment of Stress Urinary Incontinence

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Stress urinary incontinence (SUI) is a condition that affects both men and women. SUI is the involuntary leakage of urine caused by an increase in intra-abdominal pressure from activities such as exercise, coughing, laughing, or sneezing. It can significantly affect quality of life as patients avoid activities or behaviors that cause leakage. This clinical trial will compare the efficacy of the Emsella chair to sham and determine if electromagnetic technology is effective in the treatment of SUI.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

⁃ Able to read, understand, and provide written, dated, informed consent prior to screening, and be likely to comply with study protocol, including independently complete study questionnaires and communicate with study personnel about AEs and other clinically important information.

⁃ Females and males, 18 to 80 years of age, inclusive, at screening

⁃ Positive Cough or Bladder Stress Test at screening

⁃ Subject agrees not to start any new treatment (medication or otherwise) during the treatment and follow-up periods.

‣ 6\. Subject agrees to maintain a stable dose of any medication known to affect lower urinary tract function, including but not limited to anticholinergics, tricyclic antidepressants, beta-3 adrenergic agonist, or α-adrenergic blockers, throughout the treatment and follow-up periods.

‣ For Females Only:

• Subject agrees to discontinue use of bladder support devices, including but not limited to vaginal pessary, during the screening, treatment, and follow-up periods.

• If of child-bearing age and female, agree to practice approved birth-control methods (oral contraceptives, condom barrier, injection, diaphragm or cervical cap, vaginal contraceptive ring, IUD, implantable contraceptive, surgical sterilization (bilateral tubal ligation), vasectomized partner(s))

‣ For Males Only:

‣ \- Subject must be ≥ 4 months post radical prostatectomy

Locations
United States
Michigan
Corewell Health William Beaumont University Hospital
RECRUITING
Royal Oak
Contact Information
Primary
Julie Swanson, RN
Julie.Swanson2@corewellhealth.org
248-551-3551
Backup
Jennifer Giordano, RN
Jennifer.Giordano@corewellhealth.org
248-551-3517
Time Frame
Start Date: 2019-12-18
Estimated Completion Date: 2028-12
Participants
Target number of participants: 110
Treatments
Active_comparator: Emsella Chair Active Treatment
Active treatment subjects will be asked to sit on the center of the Emsella chair. The height of the chair will be adjusted until the participant's feet are on the floor. The Emsella chair will be turned on and the setting gradually increased to the subject's sensory threshold; the maximum sensation the subject can tolerate. The setting will then be decreased slightly and stay unchanged for the remainder of the treatment time. The treatment threshold should be increased with every treatment until the subject reaches 100%.
Sham_comparator: Emsella Sham Treatment
Sham subjects will be positioned on the device in the same manner as the active treatment group. The sham treatment will be provide some sensation without active HIFEM technology. The programming for the sham treatment will have an amplitude limitation, with the setting below therapeutic level (\<10% power).
Sponsors
Leads: William Beaumont Hospitals

This content was sourced from clinicaltrials.gov