Stress Urinary Incontinence Clinical Trials

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Prospective, Post-market Study of the Desara® One Single Incision Sling vs. Desara® Blue Sling Implanted Via the Transobturator Route for the Treatment of Women With Stress Urinary Incontinence

Status: Recruiting
Location: See all (15) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

A post-market study to compare the safety and effectiveness of the Desara® One Single Incision Sling (SIS), when compared to that of an FDA cleared transobturator sling over a period of 36 months.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:

• Female ≥ 18 of age.

• Subject agrees that she is willing and able to return for all study related procedures and evaluations.

• Subject has provided signed informed consent.

• Subject has stress urinary incontinence (SUI) confirmed by either supine or standing cough stress test (CST) with bladder pre-fill to subjective fullness with 200-300 mL, or with bladder fullness confirmed via ultrasound.

• Subject has confirmed stress incontinence greater than urge incontinence per MESA questionnaire.

• Subject no longer has childbearing capacity or has a negative pregnancy test and has decided to cease childbearing. Childbearing capacity to be confirmed by documented history of:

‣ A hysterectomy or

⁃ Tubal ligation or

⁃ Is otherwise incapable of pregnancy or has

⁃ Negative pregnancy test prior to study entry and has decided to cease childbearing

• Subject has been offered and either failed or refused alternative non-invasive SUI treatment options and has elected to proceed with a surgical intervention.

• Subject is eligible to undergo laparoscopic/robotic (with or without mesh) or vaginal (with or without mesh) apical, anterior or posterior prolapse concomitant surgical repair procedures (non-mesh).

Locations
United States
Arizona
Valley Urogynecology Associates, Inc.
RECRUITING
Phoenix
University of Arizona College of Medicine
NOT_YET_RECRUITING
Tucson
Florida
Urological Research Center Corp
RECRUITING
Hialeah
Idaho
Women's Health Care Associates P.A. dba Rosemark Women Care Specialists
RECRUITING
Idaho Falls
Indiana
CMB Research, LLC
RECRUITING
Newburgh
Kentucky
University of Louisville
RECRUITING
Louisville
Massachusetts
Mt. Auburn Hospital Division of Urogynecology
RECRUITING
Cambridge
Missouri
Specialty Clinical Research of St. Louis, LLC
RECRUITING
St Louis
North Carolina
Novant Health Urogynecology
RECRUITING
Charlotte
New Mexico
University of New Mexico
RECRUITING
Albuquerque
Nevada
Women's Cancer Center of Nevada
RECRUITING
Las Vegas
Ohio
The Lindner Research Center at The Christ Hospital
RECRUITING
Cincinnati
Pennsylvania
Center for Total Women's Health
RECRUITING
Lansdale
Tennessee
Center for Pelvic Health
RECRUITING
Franklin
Washington
University of Washington Medical Center
RECRUITING
Seattle
Contact Information
Primary
Vicki Gail
vgail@calderamedical.com
818-483-7602
Time Frame
Start Date: 2021-11-01
Estimated Completion Date: 2026-11
Participants
Target number of participants: 300
Treatments
Experimental: Desara® One
Single Incision Sling
Active_comparator: Desara® Blue
Transobturator Sling
Sponsors
Leads: Caldera Medical, Inc.

This content was sourced from clinicaltrials.gov