Poor Grade Aneurysmal Subarachnoid Hemorrhage Multicentric Study Group

Status: Recruiting
Location: See all (10) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY

Multicentric registry study in order to define outcome, predictors, treatment effects and their modifiers in poor grade aneurysmal subarachnoid haemorrhage patients. The search for outcome predictors is going to be subdivided into three main research areas: 1. outcome predictors in the emergency department (so called early brain injury phase). 2. outcome predictors in the neurocritical care unit (so called delayed brain injury phase). 3. Treatment strategies. Two other areas of research are identified: delayed cerebral ischemia (incidence, treatment, predictors, impact on outcome) and long term follow-up (recent evidences suggest that there may be a non-negligible proportion of poor grade subarachnoid hemorrhage patients who may benefit from substantial improvement at long-term (after 6-12 months of follow-up).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
View:

• Patients admitted to the emergency department because of aneurysmal subarachnoid hemorrhage of poor grade (IV-V) according to the WFNS classification.

Locations
Other Locations
Italy
ASST Ospedale Papa Giovanni XXIII
ACTIVE_NOT_RECRUITING
Bergamo
IRCCS Bellaria
RECRUITING
Bologna
Azienda Ospedaliera Spedali Civili
RECRUITING
Brescia
Ospedale Vito Fazzi
RECRUITING
Lecce
IRCCS San Raffaele
RECRUITING
Milan
Ospedale Maggiore della Città di Novara
RECRUITING
Novara
Azienda Ospedaliero-Universitaria di Parma
RECRUITING
Parma
Policlinico Universitario Agostino Gemelli
ACTIVE_NOT_RECRUITING
Roma
Ospedale Santissima Annunziata
RECRUITING
Taranto
Azienda Ospedaliera Universitaria Integrata
RECRUITING
Verona
Contact Information
Primary
Pietro Panni, P.I., M.D.
panni.pietro@hsr.it
+393406311389
Backup
Andrea Falini, Professor of Neuroradiology
falini.andrea@hsr.it
+39 0226432239
Time Frame
Start Date: 2021-05-25
Estimated Completion Date: 2028-12-31
Participants
Target number of participants: 800
Treatments
Poor Grade Subarachnoid Hemorrhage
All patients (prospective and retrospective) included will have to present a subarachnoid hemorrhage defined poor grade according to the WFNS scale due to the rupture of an intracranial aneurysm.~The patients are managed according to both most recent international guidelines on the specific disease (Stroke, May 2012) and according to national and institutional guidelines/protocols.
Related Therapeutic Areas
Sponsors
Collaborators: A.O. Ospedale Papa Giovanni XXIII, Azienda Ospedaliera Universitaria Integrata Verona, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Azienda Ospedaliero-Universitaria di Parma, Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Azienda Ospedaliero Universitaria Maggiore della Carita, Ospedale V. Fazzi, ASL Taranto, IRCCS Istituto delle Scienze Neurologiche di Bologna
Leads: IRCCS San Raffaele

This content was sourced from clinicaltrials.gov