Endovascular Treatment of Wide Neck Saccular Cerebral Aneurysms

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Intracranial aneurysm (IA) is a cerebrovascular disorder in which the weakness of a cerebral artery wall causes a localized dilation of the blood vessel. Intracranial aneurysm can develop and rupture, and about 85% of spontaneous subarachnoid hemorrhage (SAH) cases are caused by the rupture of Intracerebral aneurysm. Two treatments are available globally: microsurgical clipping and endovascular treatment. Endovascular treatment of Intracerebral aneurysms using detachable platinum coils ( was introduced in 1990 by Guido Guglielmi, an Italian neurosurgeon ) of different shapes and sizes are deposited into the aneurysm through a microcatheter, which reduces the blood flow and induces thrombus formation . Wide neck aneurysm defined by neck diameter greater than 4 mm or dome-to-neck ratio less than 2 Despite advances in endovascular techniques , the treatment of wide-necked aneurysms remains problematic . Endovascular treatment of intracranial aneurysms is associated with lower morbidity and mortality rates and faster recovery compared with traditional microsurgical clipping. In wide-necked Intracerebral aneurysms, complete coil embolization is often technically difficult owing to the risks of distal coil migration or coil impingement on the parent vessel . Complete coil embolization using a single microcatheter without a supporting device in cases of wide-necked Intracerebral aneurysm is technically difficult. Total occlusion rates have increased recently as a result of the advancement of supporting devices These may include balloon remodeling, use of three-dimensional (3D) coils (Russian Doll Technique), combined use of stents and coils (Stent assisted coiling), flow diverters, use of intrasaccular flow disruption (like WEB), Double catheter Technique or combined extra- and intrasaccular devices.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• All patients of spontaneous subarachnoid haemorrhage due to ruptured wide neck saccular cerebral aneurysms

• unruptured Denovo wide neck saccular cerebral aneurysms

Locations
Other Locations
Egypt
Sohag University Hospital
RECRUITING
Sohag
Contact Information
Primary
Mohmed A Awesh, assistant lecturer
mohamed.ayman@med.sohag.edu.eg
01068368550
Backup
Mohamed A Abdelaal, Professor
Time Frame
Start Date: 2022-01-01
Estimated Completion Date: 2024-12-01
Participants
Target number of participants: 40
Treatments
Experimental: Wide neck saccular cerebral aneurysms patients
Related Therapeutic Areas
Sponsors
Leads: Sohag University

This content was sourced from clinicaltrials.gov