Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia
Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study will examine the effects of varying liquid viscosity on swallow physiology in infants with oropharyngeal dysphagia and brief resolved unexplained event (BRUE) and other children with dysphagia that would be at risk for symptoms of swallow dysfunction.
Eligibility
Participation Requirements
Sex: All
Maximum Age: 21
Healthy Volunteers: f
View:
• Age 0 to 21 years
• Admitted to Boston Children's Hospital after experiencing first lifetime BRUE, or with dysphagia symptoms such that they would be at risk for BRUE or other symptoms of swallowing difficulty
• Have had videofluoroscopic swallow study performed or might have future videofluoroscopic swallow study performed.
Locations
United States
Massachusetts
Boston Children's Hospital
RECRUITING
Boston
Contact Information
Primary
Daniel R Duncan, MD, MPH
daniel.duncan@childrens.harvard.edu
617-355-0897
Time Frame
Start Date: 2021-04-01
Estimated Completion Date: 2025-08-31
Participants
Target number of participants: 200
Treatments
Placebo_comparator: Thin liquid swallows
Thin liquid swallows of formula or breastmilk or other liquid
Experimental: Slightly thick liquid swallows
Slightly thick liquid swallows of formula thickened with rice cereal or breastmilk or other liquid thickened with Gelmix
Experimental: Mildly thick liquid swallows
Mildly thick liquid swallows of formula thickened with rice cereal or breastmilk or other liquid thickened with Gelmix
Experimental: Moderately thick liquid swallows
Moderately thick liquid swallows of formula thickened with rice cereal or breastmilk or other liquid thickened with Gelmix
Related Therapeutic Areas
Sponsors
Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Leads: Boston Children's Hospital