Clinical Application of Comprehensive Intervention Scheme for Post-extubation Dysphagia Based on Neuroregulatory Mechanism

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study aims to establish a practical comprehensive intervention program for dysphagia after extubation in adult ICU patients based on the best evidence of its assessment and intervention, through expert panel discussion and Delphi method. In addition, combining the preliminary experimental results of vagus nerve stimulation applied to PED patients, we further develop a comprehensive intervention program for dysphagia after extubation based on neural regulation mechanism. Finally, the implementation effect of this PED comprehensive intervention program based on neural regulation mechanism will be verified through clinical application.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 90
Healthy Volunteers: f
View:

• Patients who met the diagnostic criteria of PED were changed to SSA score ≥24

• aged from 18 to 90 years old;

• oral or nasotracheal intubation for ≥48 hours;

• Clear mind

• Glasgow score ≥13 points, with good cooperation ability;

• There was no contraindication to oral feeding after extubation

Locations
Other Locations
China
Jinhua Municipal Central Hospital
RECRUITING
Jinhua
Contact Information
Primary
Xiuqin Feng
fengxiuqin@zju.edu.cn
13757119151
Time Frame
Start Date: 2024-03-15
Estimated Completion Date: 2025-07-30
Participants
Target number of participants: 69
Treatments
No_intervention: Control Group
During routine medical care and nursing, the responsible nurse provides daily oral care and delivers health education to patients and their caregivers regarding diet and swallowing safety. Within 8 hours after the removal of the endotracheal tube, the Standardized Swallowing Assessment (SSA) is used to screen for swallowing function. Patients are guided in food selection based on the severity of their swallowing difficulties and personal preferences, and are supplemented with enteral or parenteral nutrition or prescribed specific diets as directed by their doctor.
Active_comparator: Comprehensive Intervention Group
On the basis of the control group, a comprehensive intervention plan determined through Delphi expert consultation is implemented for PED patients. This plan includes multidisciplinary collaboration, screening and assessment, oral sensory training, oral motor training, respiratory training, and feeding management. The duration and frequency of the exercises are tailored to the patient's actual condition.
Experimental: Comprehensive Intervention Combined with Vagus Nerve Stimulation Group
On the basis of the control group, a comprehensive intervention is implemented in combination with vagus nerve electrical stimulation.
Related Therapeutic Areas
Sponsors
Leads: Second Affiliated Hospital, School of Medicine, Zhejiang University
Collaborators: Jinhua Municipal Central Hospital

This content was sourced from clinicaltrials.gov