Swallowing Difficulty Clinical Trials

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Prevalence and Characterization of Dysphagia and Dyspepsia Symptoms and Assessment of Quality of Life in Heterotopic Gastric Mucosa (HGM)

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The goal of this observational study is to learn whether heterotopic gastric mucosa (HGM) in the upper esophagus is associated with swallowing difficulties (dysphagia) in adults undergoing a medically indicated gastroscopy. The main questions it aims to answer are: * Is the presence of HGM associated with dysphagia? * Is the presence of HGM associated with dyspepsia and reduced health-related quality of life? Among participants reporting dysphagia, what is the distribution of oropharyngeal versus esophageal dysphagia, and is this related to the presence of HGM? If there is a comparison group: Researchers will compare participants with endoscopically confirmed HGM to participants without HGM to determine whether dysphagia, dyspepsia symptoms, and quality-of-life measures differ between groups. Participants will: Complete pseudonymised questionnaires about dysphagia, dyspepsia symptoms, and quality of life before the gastroscopy. Undergo the medically indicated gastroscopy as planned; the endoscopist will assess whether HGM is present based on the endoscopic appearance, and routine endoscopy findings will be documented.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Planned upper gastrointestinal endoscopy (gastroscopy) for clinical reasons (any indication)

• Age ≥ 18 years

• Written informed consent

• Ability to complete the study questionnaires prior to endoscopy

Locations
Other Locations
Germany
Knappschaftskrankenhaus Bottrop
RECRUITING
Bottrop
Contact Information
Primary
Felix Horstmann, MD
felix.horstmann@knappschaft-kliniken.de
02041151500
Time Frame
Start Date: 2026-03-24
Estimated Completion Date: 2027-07
Participants
Target number of participants: 721
Treatments
HGM present
Participants with endoscopic evidence of heterotrophic gastric mucosa
No HGM
Participants without endoscopic evidence of heterotrophic gastric mucosa
Sponsors
Leads: Knappschaft Kliniken GmbH

This content was sourced from clinicaltrials.gov