Efficacy of Nigella Sativa Oil in Eczematous Otitis Externa: A Randomized Controlled Study
Eczematous otitis externa is a common inflammatory condition of the external auditory canal characterized by itching, discomfort, discharge, and pain. Topical corticosteroids are widely used for treatment; however, alternative therapies with fewer side effects are of increasing interest. This study aims to compare the efficacy of Nigella sativa (black seed) oil and mometasone furoate ear drops in the treatment of eczematous otitis externa. Nigella sativa is a natural product with known anti-inflammatory and antimicrobial properties. In this randomized, controlled clinical trial, adult patients with eczematous otitis externa will be assigned to receive either Nigella sativa oil or mometasone furoate ear drops for 10 days. Clinical symptoms and inflammatory findings will be evaluated at baseline and after treatment. The objective of this study is to determine whether Nigella sativa oil is an effective and safe alternative to topical corticosteroid therapy.
• Adult patients aged 18 years and older
• Clinical diagnosis of eczematous otitis externa confirmed by otoscopic examination
• Presence of at least one symptom related to the affected ear (itching, discomfort, otorrhea, or pain)
• Willingness to participate and ability to provide written informed consent