Tenosynovitis Clinical Trials

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Incision Decision: A Prospective Randomized Trial Comparing Longitudinal vs. Transverse A1 Pulley Release Outcomes

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to compare two different skin incisions used in surgery to treat trigger finger in adult patients. Trigger finger occurs when a finger gets stuck or locks because of swelling of the sheath around the tendons the help move the fingers. The main questions it aims to answer are (1) Does the type of skin cut affect how well the hand works 6 weeks after surgery? (2) Does the type of skin cut affect pain levels, scar healing, and how quickly people return to their normal activities? Orthopaedic surgeons will compare a straight incision along the finger (longitudinal incision) to a incision across the crease in the palm (transverse incision) to see if one type of incision results in better recovery, less pain, a better scar, and higher patient satisfaction with the procedure. Participants who have trigger finger and are indicated for surgery will have surgery to release the pulley in their finger using one of the two types of incisions (assigned by chance). Participants will fill out questionnaires about their hand function and pain before surgery and at follow-up visits. Participants will have their scar checked and rated at about 2, 6, and 12 weeks after surgery, and report on their pain for the first few days after surgery and when they can return to work and move their finger without pain.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adult patients (age ≥ 18 years)

• Diagnosed with trigger finger (stenosing tenosynovitis) of a finger (excluding the thumb)

• Written informed consent obtained

Locations
United States
Illinois
The University of Chicago Medicine
RECRUITING
Chicago
Missouri
Washington University and Barnes-Jewish Orthopedic Center
RECRUITING
St Louis
Contact Information
Primary
Nisha N Kale, MD
kale.n@wustl.edu
314-906-2072
Backup
Jason Strezlow, MD
strelzow@wustl.edu
(314) 514-3500
Time Frame
Start Date: 2026-04-01
Estimated Completion Date: 2028-03-30
Participants
Target number of participants: 200
Treatments
Experimental: Longitudinal Incision
Participants randomized to this arm will undergo standard open A1 pulley release for trigger finger using a longitudinal incision along the axis of the finger.
Experimental: Transverse Incision
Participants randomized to this arm will undergo standard open A1 pulley release for trigger finger using a transverse incision placed in the distal palmar crease.
Related Therapeutic Areas
Sponsors
Leads: Washington University School of Medicine
Collaborators: University of Chicago

This content was sourced from clinicaltrials.gov