Testicular Cancer Clinical Trials

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Testicular Cancer Treatment: Assessing Quality of Life in Good Prognosis Metastastic Disease

Status: Recruiting
Location: See location...
Intervention Type: Drug, Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this prospective observational study is to learn about the short- and long-term effects of treating men over the age of 18 with good prognosis metastatic testicular cancer with either primary retropertioneal lymph node dissection, RPLND, (for low-stage metastastic seminoma) or three doses of chemotherapy for metastastic seminoma or nonseminoma. The main question it aims to answer is: Does primary RPLND lower the risk of side-effects compared to receiving chemotherapy?

Eligibility
Participation Requirements
Sex: Male
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients ≥18 years undergoing an open or minimally invasive primary retroperitoneal lymph node dissection (RPLND) due to seminoma stage II A/B (maximum 2 nodes, \<30 mm in any dimension)

• Patients undergoing an open or minimally invasive primary RPLND due to a retroperitoneal relapse of seminoma (maximum 2 nodes, \<30 mm in any dimension)

• Patients ≥18 years scheduled for 3-4 courses of chemotherapy due to a newly diagnosed good-prognosis metastatic germ cell tumor (nonseminoma or seminoma)

Locations
Other Locations
Sweden
Sahlgrenska University Hospital
RECRUITING
Gothenburg
Time Frame
Start Date: 2026-03-19
Estimated Completion Date: 2032-03-25
Participants
Target number of participants: 160
Treatments
Active_comparator: Surgery group
Undergoing primary RPLND
Active_comparator: Chemotherapy group
Receiving chemotherapy
Related Therapeutic Areas
Sponsors
Collaborators: University Hospital of North Norway, Haukeland University Hospital, Trondheim University Hospital, Karolinska University Hospital, Lund University Hospital, Oslo University Hospital, Uppsala University Hospital, Norrlands Universitetssjukhus, Umea, Sweden
Leads: Sahlgrenska University Hospital

This content was sourced from clinicaltrials.gov