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Comparative Study of the Quality of Life of Patients Suffering From OTOTOXICITY Due to Chemotherapy Based on Platinum Salts Fitted With a Hearing Aid Compared to Those Not Fitted.

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

There are many undesirable effects associated with platinum-based cancer treatments (renal failure, anaemia, etc.). Their administration also leads to neurosensory problems such as ototoxicity, tinnitus and reduced hearing acuity. According to a the French survey (2018), 39.7% of people suffer from hearing problems due to cancer treatments, five years after a cancer diagnosis. Improving side effects such as hypoacusis and tinnitus can significantly improve patients' quality of life and adherence to treatment. Many clinical trials proposed a medicinal solution to patients receiving platinum-based cancer treatments but none has led to a consensus on management. The aim of the study is to offer patients receiving platinum-based chemotherapy and suffering from hearing problems a hearing aid to improve their quality of life.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adult patient

• Patient currently undergoing treatment with platinum-based chemotherapy and suffering from hypoacusia consistent with the treatment or presenting a worsening of already existing hypoacusis consistent with the start of treatment with platinum-based chemotherapy

• Patient whose hypoacusis is confirmed by the audiometric test

• Patient able and willing to follow all study procedures in accordance with the protocol.

• Patient having understood, signed and dated the consent form

• Patient affiliated to the social security system

Locations
Other Locations
France
Institut de Cancerologie de Lorraine
RECRUITING
Vandœuvre-lès-nancy
Contact Information
Primary
JEAN LOUIS MERLIN, PUPH
jl.merlin@nancy.unicancer.fr
+33 3 83 65 60 62
Backup
CECILE HUIN SCHOHN, PhD
c.huinschohn@nancy.unicancer.fr
+33 3 83 59 86 07
Time Frame
Start Date: 2024-01-04
Estimated Completion Date: 2028-07-04
Participants
Target number of participants: 52
Treatments
Active_comparator: Patients suffering from chemotherapy-induced ototoxicity
Arm 1: Patients with chemotherapy-induced ototoxicity who continue their usual care.
Experimental: Patients suffring from chemotherapy-induced ototoxicity wearing hearing aids
Arm 2: Experimental group patients with chemotherapy-induced ototoxicity wearing a hearing aid to evaluate quality of life.
Related Therapeutic Areas
Sponsors
Leads: Institut de Cancérologie de Lorraine

This content was sourced from clinicaltrials.gov