Traumatic Brain Injury Clinical Trials

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Home-based Treatment of Binocular Eye Dysfunction in Veterans With Traumatic Brain Injury

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Phase 1
SUMMARY

Post-concussive vision symptoms affect many Veterans who have experienced traumatic brain injury (TBI). One common issue is trouble with near vision, a problem that may persist long after the acute injury. Double vision or difficulty focusing on close objects can affect reading and depth perception. Poor reading can interfere with academic or work performance, and loss of near focusing can affect jobs that require fine motor tasks like machining and electrical work. Even having trouble using a smartphone can have a substantial impact on both work and social function. Near vision impairment after TBI is not well understood, and treatments are limited. The goal of this project is to investigate novel virtual-reality assessments and training games to improve the near vision diagnosis and home-based rehabilitation. Restoring normal near vision function could have a large impact on the fulfillment of Veterans' educational, career, and overall life goals.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: t
View:

• U.S. Military Veteran

• Place of residence within driving distance of Cleveland, OH

• Clinical eye exam within 6 months prior to enrollment and since the most recent TBI (if applicable) and the onset of near vision symptoms (if applicable)

• Best-corrected visual acuity 20/25 or better in each eye

• Convergence insufficiency (VR-NPC \< 32 deg)

Locations
United States
Ohio
Louis Stokes VA Medical Center, Cleveland, OH
RECRUITING
Cleveland
Contact Information
Primary
Mark F Walker, MD
Mark.Walker5@va.gov
(216) 791-3800
Time Frame
Start Date: 2026-01-14
Estimated Completion Date: 2028-09-30
Participants
Target number of participants: 45
Treatments
Experimental: Group A
Intervention block followed by non-intervention block
Experimental: Group B
Non-intervention block followed by intervention block
Related Therapeutic Areas
Sponsors
Leads: VA Office of Research and Development

This content was sourced from clinicaltrials.gov