The Effect of Entry Technique on Chorioamniotic Membrane Separation in Fetoscopic Laser Photocoagulation for Twin-To-Twin Transfusion Syndrome
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of this study is to evaluate whether the entry technique surgeons use to get inside the uterus to perform fetoscopic laser photocoagulation for twin-to-twin transfusion syndrome has an effect on the rates of chorioamniotic membrane separation.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients who are eligible and elect to undergo fetoscopic selective laser photocoagulation for complicated monochorionic-diamniotic twin pregnancies with twin-to-twin transfusion syndrome.
Locations
United States
Texas
Texas Children's Hospital - Pavilion for Women
RECRUITING
Houston
Contact Information
Primary
Ahmed Nassr, MD, PhD
ahmed.nassr@bcm.edu
832-826-7449
Backup
Becky Johnson, MS, CCRP
rj2@bcm.edu
832-826-7451
Time Frame
Start Date: 2025-03-14
Estimated Completion Date: 2030-12
Participants
Target number of participants: 216
Treatments
Active_comparator: Direct Entry
Surgeons will access the uterus to perform fetoscopic laser photocoagulation by inserting a sharp trocar through a small incision in the skin. The trocar is then removed and a small tube called a cannula is left in place.
Active_comparator: Seldinger Technique
Surgeons will access the uterus to perform fetoscopic laser photocoagulation by inserting needle through a small incision in the skin and running a guide wire through the needle so a thin tube called a cannula can be placed over the wire.
Related Therapeutic Areas
Sponsors
Leads: Baylor College of Medicine