Observational Study of the Use of DBLG1 System in Real Life

Status: Recruiting
Location: See all (20) locations...
Intervention Type: Device
Study Type: Observational
SUMMARY

This study will be conducted on human subjects and is observational, prospective and uncontrolled, defined as a category 3 according to the Jardé Law (RIPH3). It is a national and multicentric study. Enrolled patients are Type 1 Diabetes (T1D) patients who receive the DBLG1 System (CE marked medical device) to be treated. Patients have their regular visits with their own clinician. No change from their usual care must and will be done, including trainings and treatment. At the end of the study, patients will keep their system for their usual care and will continue having usual follow-up visits with their clinician. Data related to their glycemia, complications and quality of life will be collected for 1 year from the beginning of their treatment. A comparison with data collected during the 2 weeks of run-in period, prior to the activation of loop mode, is planned. In case the run-in phase lasts longer than 2 weeks, data collected from the two last weeks only will be kept for analysis and comparison. The study is completed when all patients have their end of study file completed in the electronic Case Report Form (eCRF).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• patients with type 1 diabetes;

• patients who are at least 18 years old;

• patients total daily dose required must be less than 90 units (U);

• patients accepting to be treated with 100 U/mL rapid-acting insulin analog

• patients having a HbA1c ≥ 8% despite of the use of a pump for at least 6 months

• patients performing glucose self-monitoring several times ( ≥ 4) a day

• patient accepting the technology

• patients agreeing to use the system with activated loop mode during at least 75% of the

• total time of use, this will be analyzed after 1 year of use.

• patients must be affiliated to any kind of social security

Locations
Other Locations
France
Hôpital Avicenne APHP
NOT_YET_RECRUITING
Bobigny
Hôpital de la cavale blanche
NOT_YET_RECRUITING
Brest
CHU Caen
RECRUITING
Caen
Centre Hospitalier Sud Francilien
NOT_YET_RECRUITING
Corbeil-essonnes
CHU Bocage Central
RECRUITING
Dijon
Hôpital Simone Veil
NOT_YET_RECRUITING
Eaubonne
CHU Grenoble
RECRUITING
Grenoble
Groupe Hospitalier La Rochelle - Ré - Aunis
RECRUITING
La Rochelle
CHU Lille
NOT_YET_RECRUITING
Lille
Diab-e-Care
NOT_YET_RECRUITING
Lyon
Hôpital Européen
NOT_YET_RECRUITING
Marseille
Hôpital la conception, pole ENDO
NOT_YET_RECRUITING
Marseille
hôpital Nord Laennec
RECRUITING
Nantes
Hôpital Bichet Claude Bernard - APHP
NOT_YET_RECRUITING
Paris
Lariboisière - Fernand Widal APHP
NOT_YET_RECRUITING
Paris
Clinique Princess
NOT_YET_RECRUITING
Pau
CHU Reims
RECRUITING
Reims
Hôpital Pontchaillou
RECRUITING
Rennes
Hôpital civil de Strasbourg
RECRUITING
Strasbourg
Hôpital de Rangueil
NOT_YET_RECRUITING
Toulouse
Contact Information
Primary
Marion Chassouant
clinical-trial@diabeloop.fr
0767417660
Backup
Erik Huneker
erik@diabeloop.fr
Time Frame
Start Date: 2021-05-17
Estimated Completion Date: 2026-01
Participants
Target number of participants: 348
Treatments
Patient with HbA1c >= 8% despite the use of insulin pump and frequent glycemic control
only group included in the study
Authors
Sébastien Galie, Ronan Roussel
Related Therapeutic Areas
Sponsors
Leads: Diabeloop

This content was sourced from clinicaltrials.gov