Acute Glycemic Effects of Resistance Exercise in Post-menopausal Women With Type 1 Diabetes

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Regular physical activity has substantial health benefits in people with type 1 diabetes. The fear of hypoglycemia, both during and after exercise, is a major barrier to exercise in this population. A major obstacle to providing specific physical activity and exercise advice is that there are still significant gaps in the fundamental understanding of the impact of physical activity and exercise on blood glucose levels in type 1 diabetes. Women with type 1 diabetes have a substantial increase in cardiovascular risk once they have passed menopause. They may lose both bone quality and muscle mass at a faster rate with aging than those without diabetes. Overall, these changes greatly increase the risk of both cardiovascular and frailty related complications. Despite the many potential benefits of resistance exercise for post-menopausal women with type 1 diabetes, there are currently no published studies examining the effects of resistance exercise in this population. Before being able to design a clinical trial of resistance exercise, an examination of the acute effects of resistance exercise on blood glucose levels in post-menopausal women with type 1 diabetes is required. The present study will compare the glycemic effects of a low resistance, high repetition (3 sets of 15 to 20 repetitions) weight lifting program to the effects of a moderate resistance, moderate repetition (3 sets of 8 to 10 repetitions). The investigators hypothesize that the high repetition program will be associated with a bigger decline in blood glucose during exercise, but that the moderate resistance program will be associated with a higher risk of post-exercise hypoglycemia.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 45
Maximum Age: 75
Healthy Volunteers: f
View:

• female

• type 1 diabetes diagnosed for at least 1 year

• at least 12 months since last menstrual period

• physically able and willing to perform resistance exercise

• HbA1c \< 10%

• residing near Edmonton, Alberta / able to attend laboratory based sessions at the University of Alberta

Locations
Other Locations
Canada
Alberta Diabetes Institute
RECRUITING
Edmonton
Contact Information
Primary
Jane Yardley, PhD
jane.yardley@ualberta.ca
780-679-1688
Time Frame
Start Date: 2022-04-01
Estimated Completion Date: 2026-09-01
Participants
Target number of participants: 16
Treatments
Experimental: All participants
All participants will be in a single arm that undergoes two separate interventions. These interventions will include a high repetition, low resistance protocol, and a moderate repetition, moderate intensity protocol.
Sponsors
Leads: University of Alberta

This content was sourced from clinicaltrials.gov