GLYcemic COntrol and OSTEOhealth: Impact of Short-Term Glycemic Control on Skeletal Outcomes in Adults With Type 1 Diabetes
Bone damage is frequently observed in type 1 diabetes, and hyperglycemia is associated with an increased risk of fracture. This pilot study in 25 people living with type 1 diabetes aims to determine whether the introduction of an automated insulin delivery (AID) system improves bone markers through rapide optimization of glycemic control. Measurements will be taken before the start of AID, 2 months and 4 months afterwards.
• Age ≥ 18 years;
• Diagnosis of T1D or latent autoimmune diabetes of adults (LADA) for at least one year;
• Current HbA1c \>8.0% and high glycemic variability (CV \>36.0% using CGM);
• Participant planning to start using one of the commercially available AID;
• Anticipated use of the closed-loop mode;
• Willing to share CGM data during the study period.