Effect of Inulin Supplementation on Glycaemic Control and Immunological Parameters in Type 1 Diabetes (2024)
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal is to establish the effect of oral inulin supplementation on continuous glucose monitoring (CGM) metrics and immunological parameters in adults with type 1 diabetes. The investigators will perform a double-blind, randomized, placebo-controlled trial in 2x38 participants to measure effects on CGM metrics, gut microbiome composition, residual beta cell and immunological parameters.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:
• A diagnosis of type 1 diabetes, as made by their primary clinician
• A time in range of \<80% in the last four weeks before screening
Locations
Other Locations
Netherlands
Amsterdam UMC
RECRUITING
Amsterdam
Diabeter Centrum Amsterdam
RECRUITING
Amsterdam
Contact Information
Primary
Nordin Hanssen, Principal Investigator
n.m.j.hanssen@amsterdamumc.nl
+31 20-5669111
Time Frame
Start Date: 2025-05-09
Estimated Completion Date: 2027-04
Participants
Target number of participants: 76
Treatments
Experimental: Inulin
prebiotic fermentable fiber inulin
Placebo_comparator: Placebo
Placebo: Maltodextrin
Related Therapeutic Areas
Sponsors
Leads: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)