Inter- and Intraindividual Variability of the Acute Glucose Response to Exercise in Healthy Adults and People Living With Type 1 Diabetes: A Cross-over Replicate Trial

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to investigate if blood glucose responses are similar between and within individuals in response to standardized exercise in adults with and without Type 1 diabetes. The main questions it aims to answer are: What is the reproducibility of acute glycaemic responses to exercise within and between subjects in adults living with Type 1 Diabetes and in healthy adults? What is the agreement between glucose levels obtained by continuous glucose monitor (CGM) and blood glucose monitor? Participants will cycle on a cycle ergometer or rest after consuming a standardized breakfast, while glucose levels are monitored by CGM and capillary blood sampling.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: t
View:

⁃ (Healthy and T1D phases):

• age between 18 and 60 years old;

• being healthy individuals;

• engagement in physical activity at least once a week; (T1D phase):

• diagnosis of T1D for \>18 months;

• hypoglycaemia self awareness.

Locations
Other Locations
Ireland
University College Dublin
RECRUITING
Dublin
Contact Information
Primary
Veronica Merlo
veronica.merlo@ucdconnect.ie
3458479939
Backup
Katy Horner
Time Frame
Start Date: 2025-01-28
Estimated Completion Date: 2026-07-31
Participants
Target number of participants: 24
Treatments
Experimental: Exercise and Rest
At the first test visit participants will complete 30 minutes exercise on a cycle ergometer, and at the second visit they will remain at rest. Identical conditions in an identical order will be repeated the following week.
Experimental: Rest and Exercise
At the first test visit participants will remain at rest and at the second visit they will complete 30 minutes exercise on a cycle ergometer. Identical conditions in an identical order will be repeated the following week.
Related Therapeutic Areas
Sponsors
Leads: University College Dublin
Collaborators: Irish Research Council, Taighde Éireann - Research Ireland

This content was sourced from clinicaltrials.gov