Impact of a Multimodal Prehabilitation Programme on Markers of Health, Quality of Life and the Short and Long Post-surgery Recovery Period in Cancer Patients With Type 2 Diabetes

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Surgical prehabilitation refers to pre-operative interventions aimed at increasing patients' physiological reserve so that they can better cope with the stress of surgery, avoid post-operative complications and have a faster recovery after surgery. Multimodal prehabilitation combines different aspects related to a healthy lifestyle including but not limited to; physical activity, nutritional education, anxiety coping strategies, alcohol moderation and smoking cessation. Although these aspects are well known, having a cancer diagnosis and the likelihood of an incoming operation during the weeks after diagnosis, place patients in a situation where they may be more receptive to adopting lifestyle changes aimed at promoting health. Such changes could be incorporated, not just in the short-term in preparation for surgery, but also in the medium- and long-term, improving patients' wellbeing and potentially reducing the risk of cancer reoccurrence and other diseases. Although the benefits of prehabilitation before surgery are understood, the effects it may have in non-insulin-dependent Type 2 diabetes patients are unknown. This project aims to: (i) Analyse the effects of a multimodal prehabilitation programme vs. the current National Health Service (NHS) standard approach, on physical performance in cancer patients with non-insulin-dependent Type 2 diabetes prior to surgery. (ii) Explore the impact of the programme on body composition and metabolic markers. (iii) Analyse the programme adherence, markers of well-being and quality of life during a post-surgery period of up to 12 months as well as its effects on clinical outcomes.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Capacity to give consent

• Newly diagnosed with cancer

• Non-insulin-dependent Type 2 diabetes

• Awaiting surgery for cancer

Locations
Other Locations
United Kingdom
School of Human Sciences, University of Greenwich, Avery Hill Campus, Sparrows Farm (Office SF112B)
NOT_YET_RECRUITING
Eltham
King's College Hospital
RECRUITING
London
Contact Information
Primary
Fernando Naclerio, PhD
f.j.naclerio@greenwich.ac.uk
0044 2083 318441
Backup
Roberto Laza-Cagigas, MSc
r.lazacagigas@greenwich.ac.uk
0044 7597 058406
Time Frame
Start Date: 2024-01-18
Estimated Completion Date: 2025-04-30
Participants
Target number of participants: 60
Treatments
Experimental: Prehabilitation
Arm undergoing multimodal prehabilitation (physical activity, nutritional education and anxiety management) during the weeks leading up to surgery
No_intervention: Standard of care
Arm receiving standard of care (no prehabilitation)
Related Therapeutic Areas
Sponsors
Leads: University of Greenwich

This content was sourced from clinicaltrials.gov