Impact of Time-Restricted Eating (TRE) on Kidney Health (The TREK Study)
This is a clinical trial to assess how time-restricted eating (TRE) may improve kidney health and filtration patients with type 2 diabetes and increased protein content in their urine. All participants will be participating in TRE in which they follow a consistent 8-10 hour eating window everyday.
• Age: 18-75 years old
• Participants with T2DM with A1c between 6.5 and 9.0 % and on stable doses of medications who are weight-bearing and self-ambulatory.
• uACR ( urine albumin creatinine ratio) results ≥ 30 - 300 mg.
• Willingness to use smartphone for research procedures (Apple iOS or Android OS)
• Baseline eating period ≥12 hours/day and sufficient logging on the mCC app.
• Person of childbearing potential will be given a pregnancy test on study enrollment and asked to use contraception throughout the study.
• Post-menopausal and individuals on hormone replacement therapy will be included.
• Estimated Glomerular Filtration Rate (EGFR) \> 45
• If participants are on cardiovascular medications (HMG CoA reductase inhibitors (statins), other lipid-modifying drugs, anti-hypertensives) no dose adjustments will be allowed during the study period
⁃ Participants on stable doses (consistent dose for ≥3 months) of GLP-1 receptor agonists will be included.