Randomized, Double-Blind, Placebo-Controlled Crossover Clinical Trial to Evaluate the Effect of a Functional Low-Glycemic Index Carbohydrates Versus Standard Wholegrain Carbohydrates on Glycolipid Metabolism and Vascular Stress Markers in Subjects With Suboptimal Triglyceridemia
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Low-glycemic index (GI) carbohydrates help prevent type 2 diabetes and cardiovascular disease by reducing postprandial glucose, insulin spikes, inflammation, and triglyceride synthesis. They improve weight, lipid profiles, and vascular health. Our study will compare functional low-GI vs. standard wholegrain carbs in a Mediterranean diet to assess their effect on the Triglycerides-Glucose Index, a marker of metabolic and cardiovascular risk, in subjects with suboptimal triglyceride levels.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Male or female aged ≥ 18 years
• TG\>150 mg/dL
• Subjects who have the capability to communicate and to comply with the study's requirements.
• Subjects agree to participate in the study and having dated and signed the informed consent form.
Locations
Other Locations
Italy
Cardiovascular Internal Medicine Unit, IRCCS University Hospital of Bologna, Bologna, Italy
RECRUITING
Bologna
Time Frame
Start Date: 2026-02-02
Estimated Completion Date: 2026-09-29
Participants
Target number of participants: 40
Treatments
Active_comparator: Altograno® Bakery Foods
Altograno® Pasta, Pizza and Flatbrad
Placebo_comparator: Standard Whole-Grain Bakery Foods
Industrial standard whole-grain Pasta, Pizza and Flatbrad, in substitution of the same amount of carbohydrates usually eaten in a stabilized diet
Related Therapeutic Areas
Sponsors
Leads: University of Bologna