Type 2 Diabetes (T2D) Clinical Trials

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Time Restricted-eating and Metabolic Health in Patients With Type 2 Diabetes

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Time-restricted eating - where no food is consumed over a period of time - has been shown to promote weight loss and improve cardio-metabolic function. In individuals with type 2 diabetes, it is also been shown to improve glucose control. The investigators propose a randomized controlled trial to determine whether time-restricted eating is an effective therapeutic strategy that can preserve pancreatic beta-cell function and improve glycemic control early in participants with type 2 diabetes.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• Individuals with previously diagnosed BMI ≥ 25 kg/m2 and type 2 diabetes within preceding 10 years.

• Age 18 - 75 years inclusive

• Stable weight over past 12 weeks (less than 5% change in body weight) (self-reported)

• Diabetes treatment consisting of lifestyle only or metformin, dipeptidyl peptidase-4 (DPP-4) inhibitor, and sodium-glucose co-transporter 2 (SGLT2) inhibitors either as monotherapy or in combination.

• Ability to read and understand English

Locations
Other Locations
Canada
Leadership Sinai Centre for Diabetes
RECRUITING
Toronto
Contact Information
Primary
Caroline K Kramer, MD, PhD
Caroline.Kramer@sinaihealth.ca
+1-416-586-4800
Time Frame
Start Date: 2026-02-01
Estimated Completion Date: 2029-07-31
Participants
Target number of participants: 112
Treatments
Experimental: Time-restricted eating
Time-restricted eating protocol consisting of time-restricted eating with 18 hours of fasting and 6 hour window of eating (between 2 to 8 PM) every day.
Active_comparator: Standard lifestyle
Standard lifestyle recommendation as per Diabetes Canada Guidelines.
Related Therapeutic Areas
Sponsors
Leads: Mount Sinai Hospital, Canada

This content was sourced from clinicaltrials.gov