Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 2) (IRIS-CKD)
IRIS-CKD is a two-program implementation study to improve guideline-recommended screening and treatment of chronic kidney disease (CKD) in individuals with type 2 diabetes (T2D) in the United States.
• (CKD Management)
‣ Adults with type 2 diabetes (T2D)
⁃ Receiving primary care within the healthcare system, visit within 24 months (any PCP provider, including APP)
⁃ Evidence of CKD based on laboratory testing within the past 2 years (must be confirmed during screening if not checked within 3 months of enrollment):
• UACR \>300 mg/g or
∙ eGFR \<45 ml/min/1.73 m2 or
∙ UACR ≥30 mg/g with eGFR \<60 ml/min/1.73 m2
⁃ Receiving \<100% GDMT at baseline. For patients with UACR \<30 mg/g, GDMT includes sodium-glucose cotransporter-2 inhibitors (SGLT2i) therapy. For all other eligible patients, GDMT includes ACEi/ARB, SGLT2i, and Finerenone, unless contraindications for any of these therapies exist (e.g., hyperkalemia, diabetic ketoacidosis, etc.).