Comparative Effects of High-Intensity Interval Training in Pre and Postmenopausal Women With Type II Diabetes Mellitus

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Diabetes Mellitus (DM), a chronic metabolic disease-causing chronic hyperglycemia. Globally more than 90% cases are of type II diabetes mellitus (T2DM). Around 537 million adults worldwide had diabetes but according to data from Pakistan, female sufferers are marginally higher (26.4%) as compared to men (25.1%). The main causes of DM II are genetic predispositions, including consanguinity, dietary changes, urbanization and sedentary lifestyles. It is reported that postmenopausal status is linked to worsened glycemic control, increased visceral adiposity and and inflammation, and women before menopause generally have improved lipid metabolism and insulin sensitivity. HIIT provides powerful and time-efficient benefits by alternating high-intensity workouts (85-95% HR\_Max) with recovery.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 40
Maximum Age: 60
Healthy Volunteers: f
View:

• Female patients aged 40-65 years with physician-diagnosed T2DM.

• Premenopausal (regular menstruation) or postmenopausal (≥12 months amenorrhea) (self-reported).

• Participants who have not engaged in any structured exercise sessions or gym workouts in the past six months.

• Willing to follow supervised HIIT protocol and provide informed consent.

Locations
Other Locations
Pakistan
Ginnastic Health Centre, Islamabad
RECRUITING
Islamabad
Contact Information
Primary
Dr. Huma Riaz, PhD
huma.riaz@riphah.edu.pk
+923215242874
Time Frame
Start Date: 2025-09-25
Estimated Completion Date: 2026-07
Participants
Target number of participants: 45
Treatments
Experimental: High Intensity Interval Training group
The group will receive 8 weeks of High Intensity Interval Training (27 sessions, 3/week, 60-90 minutes). Progresssion for 1-4 weeks will of Workout Interval : Rest Interval will be 30 sec : 30 sec of each exercise and from week 5-8 the progression will be 30 sec : 15 sec. Both Warm-up and Cool down exercises will be of 10-15 minutes.
Active_comparator: Control group
This group will receive Resistance Exercises with alternate days 3 times per week for 8 weeks and total sessions will be 27. Both warmup and cool down will be of 10-15 minutes and progression will be increased gradually. This group will include different Resistance Exercises and the time duration will be 60-90 minutes
Related Therapeutic Areas
Sponsors
Leads: Riphah International University

This content was sourced from clinicaltrials.gov