Evaluating Atherosclerotic Disease Progression in High-Risk Patients With Diabetes Mellitus

Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY

People with type 2 diabetes have a much higher risk of heart disease. One common problem is when the blood vessels that supply the heart become narrowed or blocked by fatty deposits, called plaque. This makes it harder for blood to reach the heart and can lead to serious problems such as chest pain, heart attacks, or even death. This study will follow people with type 2 diabetes who have already had a special heart scan called a coronary CT angiography. This scan takes detailed pictures of the heart's blood vessels. The goal is to understand how heart disease changes over time in people with type 2 diabetes, by looking at repeat scans and other health information. By learning more about how plaque builds up or gets worse, researchers hope to find better ways to identify which patients are most at risk for future heart problems.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age over 18 years

• Previous completion of CCTA scan for CAD assessment

• Diagnosed with Type 2 Diabetes and currently receiving glucose lowering treatment

• Sufficient image quality of the CCTA scan (at least 2/3 vessels of sufficient quality for assessment).

Locations
Other Locations
Netherlands
Amsterdam University Medical Centers
NOT_YET_RECRUITING
Amsterdam
Cardiology Centers of the Netherlands
RECRUITING
Amsterdam
Contact Information
Primary
Willem R van de Vijver, MD
w.r.vandevijver@amsterdamumc.nl
+31205662402
Time Frame
Start Date: 2025-06-06
Estimated Completion Date: 2036-10-01
Participants
Target number of participants: 1000
Sponsors
Collaborators: INSTITUTO DE INVESTIGACION BIOMEDICA DE SALAMANCA (IBSAL), Horizon Innovative Health Initiative, Novo Nordisk A/S, Cardiology Centers of the Netherlands
Leads: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

This content was sourced from clinicaltrials.gov