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Does Computer-assist Virtual Lesion Segmentation Ushers to a Change in the Literature Consensus Regarding Mandibular Ameloblastoma Radiographic Safety Margin?. A Clinical Case Series

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Reconstruction of segmental mandibular defects is in a continuous state of evolution utilizing the recent advances in Computer-Aided Designing (CAD) and preoperative Virtual Surgical Planning (VSP). The anterior iliac crest is one of the ideal reservoirs for autogenous harvesting of a bi-cortical bone block with 1:1 cortical to cancellous bone ratio which is optimal for rapid and predictable consolidation. The aim of this study is the utility of VSP guided by CT and confirmation by histopathological analysis in achieving negative margins and preventing recurrence of mandibular ameloblastoma.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Patients with histologically confirmed ameloblastoma using a preoperative biopsy.

• Patients with ameloblastoma that require segmental mandibular continuity defect, not involving the condyle.

Locations
Other Locations
Egypt
Faculty of Dentistry, Alexandria University
RECRUITING
Alexandria
Contact Information
Primary
yehia A El-Mahallawy., PhD
yehia.el-mahallawy@alexu.edu.eg
+201007217014.
Time Frame
Start Date: 2025-01-01
Estimated Completion Date: 2027-01-01
Participants
Target number of participants: 10
Treatments
Experimental: Virtual lesion segmentation for mandibular ameloblastoma
Patient with mandibular ameloblastoma managed with virtual surgical planning \& Virtual lesion segmentation for the determination of a radiographic 10-mm safety margin.
Related Therapeutic Areas
Sponsors
Leads: Alexandria University

This content was sourced from clinicaltrials.gov