Dynamic in Vivo PET Imaging and ex Vivo Biopsies From Skeletal Muscle and Adipose Tissue to Investigate the Effects of Exercise on Insulin Resistance and Mitochondrial Energetics in Type 2 Diabetes
Status: Recruiting
Location: See location...
Intervention Type: Other, Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The overall aim of this pilot study is to investigate the effects of exercise training on skeletal muscle and adipose tissue insulin resistance in subjects with Type 2 Diabetes (T2D).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 30
Maximum Age: 65
Healthy Volunteers: t
View:
• Age 30-65 years
• Men and women
• Body mass index (BMI) between 25 and 45 kg/m2
• Sedentary (1 day or less per week of structured exercise)
• Type 2 diabetes mellitus determined by self-report or by a fasting glucose \>126mg/dl
• Weight stable (± 2 kg) for prior 3 months
• Willing to commit to the schedule of assessment visits, including the exercise intervention
Locations
United States
Florida
AdventHealth Translational Research Institute
RECRUITING
Orlando
Contact Information
Primary
Recruitment Department
Fh.tri.recruitment@adventhealth.com
407-303-7100
Time Frame
Start Date: 2021-03-30
Estimated Completion Date: 2025-06
Participants
Target number of participants: 12
Treatments
Other: All Participants
Related Therapeutic Areas
Sponsors
Leads: AdventHealth Translational Research Institute