Treating Early Type 2 Diabetes by Reducing Postprandial Glucose Excursions: A Paradigm Shift in Lifestyle Modification
A Randomized Control Trial (RCT) with 1:1 randomization of adults newly diagnosed with type 2 diabetes (T2D) to Routine Care (RC) and RC + Glycemic Excursion Minimization (RC+GEM); a program that provides RC in addition to continuous glucose monitors (CGM) within a structured, self-directed, and personalized lifestyle program called GEM. Our hypothesis is that RC+GEM will: 1) reduce hemoglobin A1c as much or more, 2) require less diabetes medication, 3) cost less, and 4) have more secondary benefits, (e.g. greater reduction in cardiovascular risk, weight, diabetes distress, depression symptoms), compared to RC alone.
• Clinical diagnosis, based on investigator assessment, of type 2 diabetes within the past 24 months
• Age ≥30.0 and ≤80 years
• Hemoglobin A1c = ≥6.5-≤11% (medical record value \<6 month-old is acceptable)
• Access to smartphone throughout the study
• Diabetes management visit with medical provider within 12 months of screening date
• If on weight altering medications (e.g., GLP-1, GIP), on a stable dose for about four weeks