Improved Adipose Tissue Storage of Dietary Fatty Acids as a New Mechanism for the Rapid Remission of Hepatic and Cardiac Metabolic Dysfunction After Bariatric Surgery
Status: Recruiting
Location: See location...
Intervention Type: Procedure, Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The present protocol aims to understand and establish whether there is a causal link between adipose tissue metabolic remodeling and Type 2 Diabetes (T2D) remission after bariatric surgery. All participants will have a bariatric surgery, divided in 2 groups: with or without T2D.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: t
View:
• Aged 18 to 65
• BMI 35 kg/m2
• Diagnosed T2D - according to Diabetes Canada diagnostics criteria.
• Diagnosed non-T2D - according to Diabetes Canada diagnostics criteria.
• Women with a negative serum pregnancy test.
Locations
Other Locations
Canada
centre de recherche du CHUS
RECRUITING
Sherbrooke
Contact Information
Primary
Frédérique Frisch
frederique.frisch@usherbrooke.ca
1-819-346-1110
Time Frame
Start Date: 2023-11-01
Estimated Completion Date: 2028-05-01
Participants
Target number of participants: 40
Treatments
Active_comparator: Control group
without T2D according to Diabetes Canada diagnostics criteria:
Experimental: group with Type 2 diabetes
with T2D according to Diabetes Canada diagnostics criteria:
Related Therapeutic Areas
Sponsors
Collaborators: Institut universitaire de cardiologie et de pneumologie de Québec, University Laval, Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Leads: Université de Sherbrooke