Hydroxychloroquine as an Adjunct Therapy in the Management of Type 2 Diabetes in Pregnancy: A Randomised Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal of this clinical trial is to compare the use of hydroxychloroquine as an adjunct to the current treatment of pregnant women with Type 2 diabetes mellitus. The main questions it aims to answer are: * Does hydroxychloroquine improve the pregnancy outcomes in women with type 2 diabetes during pregnancy? * Does hydroxychloroquine improve the inflammatory markers in women with type 2 diabetes during pregnancy? Participants will be randomised into the intervention and control group. The control group will be on standard treatment where as the intervention group will receive hydroxychloroquine as an adjunct of standard treatment
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 20
Maximum Age: 45
Healthy Volunteers: f
View:
• Singleton
• Pregnant women with a confirmed diagnosis of type 2 Diabetes Mellitus
Locations
Other Locations
Malaysia
Antenatal clinic, UKM Medical Centre
RECRUITING
Cheras
Contact Information
Primary
Rahana Abdul Rahman, MD
drrahana@ukm.edu.my
039145
Time Frame
Start Date: 2024-03-24
Estimated Completion Date: 2027-01-01
Participants
Target number of participants: 56
Treatments
Experimental: Hydroxychloroquine group
Oral hydroxychloroquine 200mg daily will be prescribed to women in this group from recruitment (14-20 weeks) till delivery, in addition to their standard treatment
No_intervention: Standard treatment group
Women will receive standard treatment for diabetes such as metformin and insulin.
Related Therapeutic Areas
Sponsors
Leads: National University of Malaysia