Exercise Training During Hospitalization in Patients with Type 2 Diabetes - a Phase 1 Trial
Type 2 Diabetes (T2D) is associated with prolonged hospitalization and an increased risk of readmission. Moreover, sedentary behavior and poor glycemic control may contribute to disease severity and mortality. The inactivity during hospitalization is particularly concerning in T2D patients, due to the negative effect on glucose metabolism and secondary loss of skeletal muscle mass, which can further disrupt glucose regulation. However, there are no exercise guidelines for hospitalized T2D patients. To address this gap, a feasibility study will be conducted examining the effectiveness of incorporating resistance training into hospital care for T2D patients. For the feasibility study, 24 patients with T2D or prediabetes will be recruited from the Department of Infectious Diseases at Rigshospitalet and Hvidovre Hospital and randomized to 4 weeks of resistance training for 30 minutes per day or standard treatment. If the participants are discharged they will be offered online-training sessions. During the hospitalization a continuous glucose monitor will be applied and an accelerometer during the full intervention. At baseline, discharge and at follow-up, extensive testing will be performed.
• T2D or prediabetes defined as at least one of the following
‣ ICD-10 diagnosis of T2D (DE11.x)
⁃ HbA1c \> 48 at time of admission
⁃ Use of type 2 antidiabetic medicine (excluding SGLT2 inhibitors)
⁃ HbA1c ≥ 42 within 3 months of admission (prediabetes)
• Hospitalized with an infection
• Expected residual hospitalization time of at least three days
• At least 18 years of age
• Able to perform exercises in the booklet Syg men sun dog aktiv